In addition, phytochemical analyses of N. Black cumin seeds also contain significant levels of iron, copper, zinc, phosphorus, calcium, thiamin, niacin, pyridoxine, and folic acid. Among various amino acids identified, glutamate, arginine, and aspartate while cysteine and methionine were the major and minor amino acids, respectively. The nutritional composition reported from different sources revealed 20-85% of protein, 38.20% of fat, 7-94% of fiber, and 31.94% of total carbohydrates. The maximal nutritional value of black cumin can be linked to the presence of substantial amount of vegetable protein, fiber and minerals, and vitamins. (Ranunculaceae) has been considered one of the most treasured nutrient-rich herb in history around the world and numerous scientific studies are in progress to validate the traditionally claimed uses of small seed of this species. Among several medicinal plants, Nigella sativa L. The development of new products from natural sources is also encouraged because it is estimated that, of the 300,000 herbal species that exist globally, only 15% have been explored for their pharmacological potential. Recently, the usage of phytomedicine has been amplified dramatically for numerous ailments because of not only their easy accessibility and low cost but also the belief that natural remedies have fewer harmful effects as compared to synthetic medicines. In line with the new progress in the area of optimum nutrition, nowadays there is a resurgence of interest in the use of plants as a source of food and medicine. According to the World Health Organization (WHO), more than three-fourths of the communities in resource-limited countries rely upon medicinal plants for their primary health care needs because more than 60% of the societies are unable to have access and/or afford allopathic medicines. Plants have long been used as a basis of traditional remedies in the history of mankind and also act as sources of modern medicines. sativa seed and its oil so as to explore functional food and nutraceutical potential of this valued herb. The present review focuses on the profile of high-value components along with traditional medicinal and biological principles of N. A number of pharmaceutical and biological properties have been ascribed to seeds of N. Besides, when combined with different conventional chemotherapeutic agents, it synergizes their effects resulting in reducing the dosage of concomitantly used drugs with optimized efficacy and least and/or no toxicity. Moreover, the strong antioxidant property of this valued seed has recently gained increasing attention with regard to its potential role as dietary supplement with minimal side effects. sativa against HIV/AIDS can be explored as an alternative option for the treatment of this pandemic disease after substantiating its full therapeutic efficacy. In spite of limited studies conducted so far, the promising efficacy of N. So far, numerous studies demonstrated the seed of Nigella sativa and its main active constituent, thymoquinone, to be medicinally very effective against various illnesses including different chronic illness: neurological and mental illness, cardiovascular disorders, cancer, diabetes, inflammatory conditions, and infertility as well as various infectious diseases due to bacterial, fungal, parasitic, and viral infections. sativa) has been used in different civilization around the world for centuries to treat various animal and human ailments.
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